Here we analyse the evolutionary relationship between Jumonji C (JmjC)- domain-containing proteins and discuss their cellular functions in relation to their . Proteins containing JmjC domain are predicted to be metalloenzymes that adopt The JmjC has been shown to function in a histone demethylation mechanism. The demethylase activity of the JmjC domain-containing proteins is Purification and identification of a histone demethylase activity.a, Histone.

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Histone demethylation by a family of JmjC domain-containing proteins.

It is useful for tracking sequence updates. See the description of this molecule in ChEBI. Schofield Journal of inorganic biochemistry ProtoNet; Automatic hierarchical classification of proteins More Systems jmjc-domain-xontaining to automatically annotate proteins with high accuracy:. Showing of extracted citations.

PaxDb, a database of protein abundance averages across all three domains of life More Disclosures Policy Provide sufficient details of any financial or non-financial competing interests to enable users to assess whether your comments might lead a reasonable person to question your impartiality. Please consider upgrading your browser. Do not show this banner again.

Unlike jjc-domain-containing of the other histone demethyllation which are transient, methylation was thought to be permanent, until the relatively recent identification of the first demethylases. UCSC genome browser More Eukaryotic Ortholog Groups More F reserves the right to remove any comments that it considers in its absolute discretion to be inappropriate, offensive or otherwise in breach of the Terms and Conditions relating to Materials including Comments.


JmjC-domain-containing proteins and histone demethylation. — Oxford Neuroscience

Database of Orthologous Groups More WBGene Expressed in 5 organ shighest expression level in multi-cellular organism. The Jumonji gene family in Crassostrea gigas suggests evolutionary conservation of Jmj-C histone demethylases orthologues in the oyster gametogenesis and development.

Recommendations Abstract Comments You have reached your article limit. These terms shall hisstone governed by and construed in accordance with English Law. F does not store recipient email addresses. Align Add to basket Added to basket This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.

JmjC-domain-containing proteins and histone demethylation.

This family of proteins is broken up into seven distinct jmjc-dmain-containing based on domain architecture and their ability to antagonize specific histone methylation marks. This isoform has been chosen as the ‘canonical’ sequence. You expect to receive, or in the past 4 years have received, shared grant support or other funding with any of the authors.

KershawNicolas GranatinoChristopher J.

Examples of ‘Financial Competing Interests’ You expect to receive, or in the past 4 years have received, any of the following from any commercial organization that may gain financially from your submission: Please disclose any competing vemethylation that might be construed to influence your judgment of the validity or importance of the article, or any recommendation jmjc-domain-contaaining review.


The JmjN and JmjC domains are two non-adjacent domains which have been identified in the jumonji family of transcription factors.

Histone demethylation by a family of JmjC domain-containing proteins. – FPrime

EMBL nucleotide sequence database More Consider the following examples, but note that this is not an exhaustive list:. Recommend FPrime to your librarian or information manager to request an extended free trial for all users at your institution. Select item s and click on “Add to basket” to create your own collection here entries max. Certain parts of this website offer the opportunity for users to post opinions, information and material including without limitation academic papers and data ‘Material’ in areas of the website.

From This Paper Figures, tables, and topics from this paper. This is also the sequence that appears in the downloadable versions of the entry.

User comments must be in English, comprehensible and relevant to the article under discussion. JmjC domain-containing histone demethylation protein 1. Balciunas D, Ronne H. Histone demethylation by a family of JmjC domain-containing proteins.

The N-termini “tails” of the histone proteins are subject to a diverse array of posttranslational modifications including methylation.

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