ouse strains expressing the site-. specific recombinase Cre (or Flp). facilitate c onditional ablation of gene. function when one or several exons of the. gene of. Generalized lacZ expression with the ROSA26 Cre reporter strain. Soriano P Nat Genet. 21 (1): PMID: · DOI/ Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo. Pfeifer A, Brandon EP, Kootstra N, Gage FH, Verma IM.
|Published (Last):||5 January 2013|
|PDF File Size:||5.60 Mb|
|ePub File Size:||14.55 Mb|
|Price:||Free* [*Free Regsitration Required]|
A decade ago, RUNX3, a gene that resides on human chromosome 1p GC studies that atrain to identify relevant oncogenes and tumor suppressor genes TSGs are essential for devising effective new therapies.
Soriano P Nat Genet.
Generalized lacZ expression with the ROSA26 Cre reporter strain. – Abstract – Europe PMC
Creative Data Solutions CDS reporteer a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches. Find labs, cores and centers Find and connect with people Find reagents and information. Vanderbilt University is committed to principles of equal opportunity and affirmative action.
All Rights Reserved to Vanderbilt University. Journal of Cancer TherapyVol.
Scientific Research An Academic Publisher. Evaluation of cloud seeding project in Yazd Province of Iran using historical regression method case study: Gastric cancer GC is a major cause of cancer mortality. To be a TSG that protects normal cells against malignancy, the gene must be expressed in the normal tissue from which the cancer arose and its loss or inactivation reportsr contribute to cancer development.
Plasmid vector based generation of transgenic mesenchymal stem cells with stable expression of reporter gene in caprine. Connections 1 This publication is referenced by other Labnodes entities: RUNX3 promoter methylation, which has been reported to be a frequent event in GC, is not relevant to its alleged TSG function, since the gene is already silent in normal gastric epithelium.
Stellor Khodo, PhD Medicine. Studies show unequivocally that RUNX3 is not expressed in normal gastric epithelium and that it fails generalizer fulfill all other premises of a TSG.
View secure login page. Hydroxypropylmethylcellulose gel application delays Der p 1 diffusion in vitro. Yazd 1 cloud seeding project, The true targets for GC therapy are discussed below.
Generalized lacZ expression with the ROSA26 Cre reporter strain – Semantic Scholar
Those are genes frequently lost or amplified in GC and are well known for their tumor suppressive or oncogenic activity, respectively. Featured community Creative Data Solutions CDS is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics reportre bioinformatics approaches.
We have detected that you are using some form of ad-blocking or filtering. Please consider white-listing Labnodes since 1 ad-blockers like uBlock break Labnodes functionality and 2 Labnodes does not serve ads.