BACKGROUND: Flavobacterium meningosepticum is an uncommon pathogen causing nosocomial pneumonia and meningitis in newborns. It is usually. Elizabethkingia meningoseptica is a gram-negative rod-shaped bacterium widely distributed in . Flavobacterium meningosepticum King, (Approved Lists, ); Chryseobacterium meningosepticum (King, ) Vandamme et al., . Flavobacterium meningosepticum is a gram negative, opportunistic organism which has been implicated in a number of outbreaks of sepsis and meningitis in.
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Journal List Antimicrob Agents Chemother v. CSF cell count and chemistry could not be done due to the small sample obtained. Indian J Med Res. Head circumference had increased to 44 cm from V Q 12H alongwith ceftazidime mg I. Version format compliance Version 1. Hypoalbuminemia, increased pulse rate at the onset of infection, and central venous line infection were associated with a poor outcome.
Although the organism was resistant to rifampicin and ceftazidime on disc diffusion testing, ceftizoxime was not readily available and an interim therapy was initiated with these drugs. Most of these are classic drugs for gram positive bacteria and not routinely tested on gram negative bacteria. Ventricular CSF was examined Table and found to be abnormal with Grain negative bacilli seen on gram stain. Serum bilirubin had risen to total of Blood and CSF cultures remained negative, but as they were obtained after the institution of antimicrobial therapy, antibiotics were continued.
Eighteen isolates of F meningosepticum were identified from 16 patients. These two can be distinguished by the indole test or the Pyr testboth of which should be clearly negative for B.
Flavobacterium meningosepticum bacteremia: an analysis of 16 cases.
Some of the outbreaks have been linked to sources like contaminated lipid stock bottles, contaminated venous mdningosepticum lines and nutritional solution, and tap water. King who isolated Kingella kingae in was studying unclassified bacteria associated with pediatric meningitis at the Centers for Disease Control and Prevention in Atlanta, when she isolated an organism Flxvobacterium group IIa that she named Flavobacterium meningosepticum Flavobacterium means “the yellow bacillus ” in Latin ; meningosepticum likewise means “associated with meningitis and sepsis “.
About Us Contact Us. Cranial computerized tomography was performed on seventh hospital day and flavobscterium dilatation of ventricular system with contrast enhancement suggestive of ventriculitis. The infection is usually associated with a very high meningoseptixum 3,4.
View more in-depth experimental data. Retrieved from ” https: In all Journals Diazepam was used to control seizures and as sepsis was suspected, cefotaxime and amikacin were given intravenously. Exchange transfusion was performed and the baby was mechanically ventilated. The patient started feeding and gaining weight. Human cerebrospioal fluid phar macokinetica and treatment of bacterial meningitis with ceftizoxime.
The presence of the heterotetrameric structure in the crystals is significant because dimerization of precursors has been suggested in the human enzyme to be a prerequisite to trigger autoproteolysis. There were 10 men and six women, with a mean age of Inthe American bacteriologist Elizabeth O.
These enzymes are activated from a single chain precursor by intram The first epidemic outbreak of meningossepticum in the newborn in South America. Of them, seven were suspected to have acquired the pathogen from diagnostic or therapeutic procedures. This journal is a member of and subscribes to the principles of the Committee on Publication Ethics.
This article has been cited by other articles in PMC. They do not form sporesand require oxygen to survive. Forty-eight hours developed seizures involving the Petechiae were seen over the extremities and baby vomited altered blood. We ,eningosepticum describe the structure of a mutant wherein the Falvobacterium nucleophile Thr is substituted by a cysteine. Nosocomial meningitis of the newborn caused by a flavobacterium. Ventricular CSF cultured at this time was sterile. The baby was assessed to be small for gestational age with postnatal sepsis and patent ductus arteriosus.
Flavobacterium meningosepticum was isolated in two cases 2. It may be normally present in fish and frogs ; while it may be isolated from chronic infectious states, as in the sputum of cystic fibrosis patients.
Epidemic meningitis of the newborn caused by flavobacteria. Funding is constantly needed for new projects and to update and refurbish existing facilities. Studies on a group of previously unclassified bacteria associated with meningitis in infants.
Please update to a newer version or download a new web browser, such as Chrome or Firefox. Lee, EL, Robinson, M.
Elizabethkingia meningoseptica is a gram-negative rod-shaped bacterium widely distributed in nature e. Meningitis caused by Flavobacterium meningosepticum. Elizabethkingia meningoseptica KingKim et al. Under a microscope, E.